Performance Evaluation of Infusion Systems for Red Blood Cell Transfusion
10.15263/jlmqa.2019.41.3.161
- Author:
Min Sun KIM
1
;
Jin Seok KIM
;
Eunyoung LIM
;
Hongchul PARK
;
Sang Hyun HWANG
;
Heung Bum OH
;
Dae Hyun KO
Author Information
1. Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. daehyuni1118@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Electromechanical infusion system;
Accuracy;
Hemolysis
- MeSH:
Erythrocyte Transfusion;
Erythrocytes;
Hematocrit;
Hemolysis;
Humans;
Infant;
Infant, Newborn;
Korea;
L-Lactate Dehydrogenase;
Plasma;
Potassium
- From:Journal of Laboratory Medicine and Quality Assurance
2019;41(3):161-165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Transfusion in neonates and infants can be performed using an electromechanical infusion system that has appropriate accuracy in terms of flow rate, volume, and bolus. However, there are no infusion systems approved for transfusion in Korea. In this study, we evaluate the performance of two electromechanical infusion systems for transfusion in pediatric patients. METHODS: We tested two systems, Baxter and Terumo, using 9 units of leukocyte-filtered red blood cells. The blood samples were delivered through the systems at constant speeds of 10, 30, and 100 mL/hr, and the accuracy in terms of the delivered volume was estimated. Before and after infusion, hemoglobin, hematocrit, plasma hemoglobin, potassium, and lactate dehydrogenase levels were measured in each sample. The percentage of hemolysis (%Hemolysis) was calculated to evaluate the safety of the infusion systems. RESULTS: For Terumo, the mean error rate of the infused volume was less than 5%. We expect that Terumo can transfuse blood at a volume close to the set volume. Further, both infusion systems showed acceptable %Hemolysis levels (mean±standard deviation: Terumo, 0.14±0.04; Baxter, 0.17±0.06). CONCLUSIONS: Both infusion systems can be used safely for transfusion in pediatric patients.
