Cribriform-morular Variant Papillary Carcinoma associated with Familial Adenomatous Polyposis.
10.16956/kjes.2005.5.2.109
- Author:
Jandee LEE
1
;
Sihoon LEE
;
Chi Young LIM
;
Kee Hyun NAM
;
Hang Seok CHANG
;
Woung Youn CHUNG
;
Cheong Soo PARK
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Cribriform-morular variant;
Papillary thyroid carcinoma;
Familial adenomatous polyposis
- MeSH:
Adenomatous Polyposis Coli*;
Carcinoma, Papillary*;
Colon;
Female;
Humans;
Incidence;
Mass Screening;
Recurrence;
Thyroid Gland;
Thyroid Neoplasms
- From:Korean Journal of Endocrine Surgery
2005;5(2):109-113
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cribriform-morular variant (CMV) is a rare histologic subtype of papillary thyroid carcinoma (PTC). Patients with familial adenomatous polyposis (FAP) could be associated with several comorbid diseases including thyroid cancer. Most thyroid cancers in them are PTCs, but infrequently CMV types can occur. The FAP concomitant CMV-PTCs are found predominantly in young women and reveals lower recurrence rate. Moreover, this variant shows circumscribed morphology and rarely metastasizes to node. Because the incidence of thyroid carcinoma is higher than that in general population, comprehensive evaluation of thyroid gland should be performed for the patients with FAP. Because thyroid cancer could be first manifestation of FAP, colonic screening should be considered in CMV-PTC patient. We report two cases of CMV-PTCs concurrent with FAP.
