A Case of Subclinical Hypothyroidism Associated with Turner's Syndrome
- Author:
In Kwon HAN
;
Jung Gil LEE
;
Sun Wha LEE
;
Seong Kyu LEE
;
Chan Moon PAK
;
Ho Yeon CHUNG
- Publication Type:Case Report
- Keywords:
Turner's syndrome;
Subclinical hypothyroidism
- MeSH:
Amenorrhea;
Cells, Cultured;
Estrogens;
Female;
Humans;
Hypothyroidism;
Medroxyprogesterone;
Menstruation;
Mosaicism;
Plasma;
Thyroxine;
Triiodothyronine;
Turner Syndrome;
Young Adult
- From:Journal of Korean Society of Endocrinology
1994;9(1):35-38
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently it is known that Turner's syndrome is frequently associated with hypothyroidism. We report a case of Turner's syndrome associated with subclinical hypothyroidism. A 23-year-old female was admitted to the hospital with complaints of amenorrhea and short stature. She had a mosaicism of 45, X0/46, Xi(X_q) in the cell, cultured from the peripheral blood. The plasma thyroxine and triiodothyronine were normal and there was no clinical symptom of hypothyroidism. But the thyroid-stimulating hormone(TSH) concentration was unusually higher(184 uU/L). She has been treated with the cyclic therapy of conjugated estrogen and medroxyprogesterone, in addition to the thyroxine replacement therapy. After 2 months, the menstruation was restored and TSH was normalized.