A Case of Premature Coronary Atherosclerosis Associated with Systemic Lupus Erythematosus.
10.4070/kcj.1995.25.3.691
- Author:
Yoon Gi MOON
;
Yong Joo KIM
;
Doo Soo JEON
;
Dong Heon KANG
;
Man Young LEE
;
Ki Bae SEUNG
;
Chang Sung CHAE
;
Ho Yeon KIM
;
Jae Hyong KIM
;
Soon Jo HONG
;
Kyu Bo CHOI
- Publication Type:Case Report
- Keywords:
SLE;
Coronary atherosclerosis
- MeSH:
Adult;
Arteritis;
Atherosclerosis;
Coronary Artery Disease*;
Coronary Vessels;
Female;
Heart;
Heart Diseases;
Humans;
Lupus Erythematosus, Systemic*;
Myocardial Ischemia;
Pericarditis;
Spasm;
Thrombophilia
- From:Korean Circulation Journal
1995;25(3):691-697
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cardiac involvement in systemic lupus erythematosus(SLE) is common and has been reported in more than 50% of the patients at the same stage during their illness. SLE can affect the heart in a number of ways;myocarditis, pericarditis, aortic insufficiency, hypertensive heart disease, and coronary arteritis. In recent years, with prolonged survival and improvement in diagnostic modalities, the cardiovascular manifestations of SLE have become more apparent. Coronary artery disease has a number of possible pathogenic mechanisms;atherosclerosis, coronary arteritis, spasm, and hypercoagulability. For management purposes, differentiation between arteritis and artheroslerosis is important. Atherosclerosis in the coronary as well as other vessels appears to be accelerated by SLE. Cardiovascular care to the SLE patients should be emphasized, because corticosteroid treatment and auto-immune mechanisms of SLE are able to promote the atherosclerosis of coronary arteries. We report 36-year-old otherwise healthy female with SLE who presented with severe ischemic heart disease requiring coronary by-pass surgery.
