Rise of the Visible Monkey: Sectioned Images of Rhesus Monkey
- Author:
Beom Sun CHUNG
1
;
Chang Yeop JEON
;
Jae Won HUH
;
Kang Jin JEONG
;
Donghwan HAR
;
Kyu Sung KWACK
;
Jin Seo PARK
Author Information
- Publication Type:Original Article
- Keywords: Cross Sectional Anatomy; Magnetic Resonance Imaging; Monkey; Primates; Visible Human Project
- MeSH: Anatomy, Cross-Sectional; Brain; Dataset; Female; Haplorhini; Head; Humans; Macaca mulatta; Magnetic Resonance Imaging; Primates; Skin; Tomography, X-Ray Computed; Veterinary Medicine
- From:Journal of Korean Medical Science 2019;34(8):e66-
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Gross anatomy and sectional anatomy of a monkey should be known by students and researchers of veterinary medicine and medical research. However, materials to learn the anatomy of a monkey are scarce. Thus, the objective of this study was to produce a Visible Monkey data set containing cross sectional images, computed tomographs (CTs), and magnetic resonance images (MRIs) of a monkey whole body. METHODS: Before and after sacrifice, a female rhesus monkey was used for 3 Tesla MRI and CT scanning. The monkey was frozen and sectioned at 0.05 mm intervals for the head region and at 0.5 mm intervals for the rest of the body using a cryomacrotome. Each sectioned surface was photographed using a digital camera to obtain horizontal sectioned images. Segmentation of sectioned images was performed to elaborate three-dimensional (3D) models of the skin and brain. RESULTS: A total of 1,612 horizontal sectioned images of the head and 1,355 images of the remaining region were obtained. The small pixel size (0.024 mm × 0.024 mm) and real color (48 bits color) of these images enabled observations of minute structures. CONCLUSION: Due to small intervals of these images, continuous structures could be traced completely. Moreover, 3D models of the skin and brain could be used for virtual dissections. Sectioned images of this study will enhance the understanding of monkey anatomy and foster further studies. These images will be provided to any requesting researcher free of charge.
