Obstetrical Outcomes of Amniocentesis or Chorionic Villus Sampling in Dichorionic Twin Pregnancies
10.3346/jkms.2019.34.e142
- Author:
Mi Sun KIM
1
;
Myoung Jin MOON
;
Sukho KANG
;
Sang Hee JUNG
;
Sung Woon CHANG
;
Hyo Jin KI
;
Bohye KIM
;
Eunhee AHN
Author Information
1. Department of Obstetrics and Gynecology, CHA Bundang Medical Center, Seongnam, Korea. bestob@chamc.co.kr
- Publication Type:Original Article
- Keywords:
Amniocentesis;
Chorionic Villus Sampling;
Obstetrical Outcome;
Twin Pregnancy
- MeSH:
Amniocentesis;
Chorion;
Chorionic Villi Sampling;
Chorionic Villi;
Diagnostic Tests, Routine;
Female;
Fetus;
Gestational Age;
Humans;
Pregnancy;
Pregnancy, Twin;
Retrospective Studies;
Twins
- From:Journal of Korean Medical Science
2019;34(18):e142-
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Under certain situations, women with twin pregnancies may be counseled to undergo invasive prenatal diagnostic testing. Chorionic villus sampling and amniocentesis are the two generally performed invasive prenatal diagnostic tests. Studies comparing procedure-related fetal loss between first-trimester chorionic villus sampling and second-trimester amniocentesis in twin pregnancies are limited. This study aimed to evaluate the procedure-related fetal loss and the obstetrical outcomes of these two procedures, chorionic villus sampling and amniocentesis in twin pregnancies. METHODS: The data from dichorionic-diamniotic twin pregnancies on which first-trimester chorionic villus sampling (n = 54) or second-trimester amniocentesis (n = 170) was performed between December 2006 and January 2017 in a single center were retrospectively analyzed. The procedure-related fetal loss was classified as loss of one or all fetuses within 4 weeks of procedure, and overall fetal loss was classified as loss of one or all fetuses during the gestation. The groups were compared with respect to the procedure-related and obstetrical outcomes. RESULTS: The difference in proportion of procedure-related fetal loss rate (1.9% for chorionic villus sampling vs. 1.8% for amniocentesis; P = 1.000) and the overall fetal loss rate (7.4% for chorionic villus sampling vs. 4.7% for amniocentesis; P = 0.489) between the two groups was not significant. The mean gestational ages at delivery were not statistically significant. CONCLUSION: Both the overall fetal loss rate and the procedure-related fetal loss rate of chorionic villus sampling and amniocentesis in dichorionic twin pregnancies had no statistical significance. Both procedures can be safely used individually.
