Clinical Consideration of Prednisolone Induced Cataract.
- Author:
Kyu Seop KIM
1
;
Choun Ki JOO
Author Information
1. Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea. ckjoo@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Cataract;
Prednisolone;
Systemic steroid
- MeSH:
Cataract*;
Prednisolone*
- From:Journal of the Korean Ophthalmological Society
2004;45(5):732-735
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this paper was to examine the correlation between the development of posterior subcapsular cataract and the dosage and duration of systemic steroid therapy. METHODS: Twenty-two eyes which underwent cataract surgery at our ophthalmologic department were enrolled, along with 20 randomly selected eyes, which received prednisolone therapy at least for 1 year. We examined prednisolone dosage, duration and systemic disorders. We compare daily prednisolone dosage, and duration between the subcapsular opacity group and the non-subcapsular opacity group. SPSS, with 2 way- ANOVA system, was used for statistical analysis. RESULTS: The development of posterior subcapsular cataract was correlated with the daily prednisolone dosage, but not with the duration of prednisolone therapy (p<0.05). CONCLUSIONS: Careful attention to the daily steroid dosage is required to prevent posterior subcapsular cataract formation.
