Analysis of Autologous Blood Injection for Late-onset Filtering Bleb Leak after Trabeculectomy.
- Author:
Eui Yun JUNG
1
;
Eun Cheul LEE
Author Information
1. Department of Ophthalmology, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Korea. erung@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Autologous blood injection;
Bleb leak;
Trabeculectomy
- MeSH:
Anterior Chamber;
Blister*;
Female;
Glaucoma;
Humans;
Intraocular Pressure;
Male;
Retrospective Studies;
Trabeculectomy*;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2004;45(5):776-782
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the effect of autologous blood injections for late-onset filtering bleb leakage after trabeculectomy METHODS: Retrospective chart review was done on 15 patients 16 eyes that had autologous blood injection(s) for filtering bleb leak occurring later than 2 months after trabeculectomy at the Masan Samsung Hospital. Successful treatment was defined as resolution of the bleb leak and no need for additional glaucoma medications. Failure was defined as a persistent bleb leak, intraocular pressure greater than 21 mm Hg, or the occurrence of a vision-threatening event related to the procedure. RESULTS: The mean age of the patients was 53.9 years old (38~74 years). Ten eyes were men (62.5%) and 6 were women (37.5%). Sixteen eyes of 15 patients had autologous blood injection for filtering bleb leak and were followed for a mean of 12.7 months (SD, 5.8; range, 3 to 25 months). Eleven eyes (68.7%) were classified as failures because of persistence of the leak. Five eyes (31.3%) had an initially successful outcome, but the success rate decreased over time as bleb leaks recurred in one of the five eyes at 3 month. Mean intraocular pressure increased from 4.9mmHg at pretreatment to 7.6 mmHg at final examination (P<0.05). Snellen visual acuity (with correction or pinhole) remained within 2 lines of pretreatment acuity in 12 eyes (75%). Blood seepage into the anterior chamber after autologous blood injection was the common complication, but it was transient. CONCLUSIONS: Although it showed limited success, autologous blood injection for late-onset bleb leak may be considered as a supportive measure before preforming invasive incisional surgery.
