Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication
10.22650/JKCNR.2019.25.2.170
- Author:
Su Jin LEE
1
;
Hyeon Ok JU
Author Information
1. RN, Department of Nursing, Dong-A University Hospital · Graduate Student, Department of Nursing, Dong-A University, Korea.
- Publication Type:Original Article
- Keywords:
Systemic Lupus Erythematosus;
Depression;
Self-Efficacy;
Perception;
Medication Adherence
- MeSH:
Depression;
Humans;
Lupus Erythematosus, Systemic;
Medication Adherence;
Negotiating;
Nursing;
Outpatients;
Tertiary Care Centers
- From:
Journal of Korean Clinical Nursing Research
2019;25(2):170-178
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with systemic lupus erythematosus. METHODS: 128 patients aged ≥19 years, who were regular outpatients or admitted patients diagnosed with systemic lupus erythematosus at a tertiary hospital in B city, participated in this study. Data were collected by using a self-administered questionnaire. Testing of mediating effects was analyzed by a parallel redundant mediated model using the PROCESS macro for SPSS version 3.3. RESULTS: They scored an average of 16.71±11.13 for depression, 694.14±170.68 for self-efficacy, 3.05±4.60 for the belief about medication, and 90.14±15.37 for medication adherence. The direct effect of depression on medication adherence was not statistically significant, but the indirect effects of depression mediated with self-efficacy and belief about medication were statistically significant. CONCLUSION: It is necessary to develop and apply a nursing intervention program that can not only relieve depression but also promote self-efficacy and the belief about medication with the objective of improving medication adherence among patients with systemic lupus erythematosus.
