Role of Particulate Matter in Skin Inflammation
- Author:
Madeeha AROOJ
1
;
Young Sang KOH
Author Information
- Publication Type:Review
- Keywords: Particulate matter; Pro-inflammatory cytokines
- MeSH: Collagen; Cytokines; Dermatitis; Environmental Pollution; Humans; Inflammation; Oxidative Stress; Particulate Matter; Psoriasis; Skin Neoplasms; Skin
- From:Journal of Bacteriology and Virology 2019;49(2):89-92
- CountryRepublic of Korea
- Language:English
- Abstract: Environmental pollution is a major global problem that affects human health. Among different types of environmental pollution, particulate matter (PM) has a key role. As PM spreads in the air so it causes different bronchial and skin inflammatory conditions. PM increases oxidative stress by ROS production and pro-inflammatory cytokines. As a result, matrix metalloproteinase is also produced, such as MMP1, MMP9 and MMP2 that is a known major cause of skin collagen degradation. Recently it has been shown that the PM worsens allergic conditions like dermatitis, psoriasis, and skin cancer. Different extensive efforts have been made across the globe to control this PM.
