A Case of Pediatric Acute Lymphoblastic Leukemia with Trisomy 5 as a Sole Chromosomal Anomaly: A Prognostic Significance
10.15264/cpho.2019.26.2.91
- Author:
Young Hwan CHO
1
;
In sang JEON
Author Information
1. Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea. isjeon@gilhospital.com
- Publication Type:Case Report
- Keywords:
Trisomy 5;
Acute lymphoblastic leukemia;
Prognosis;
Pediatrics
- MeSH:
Cytogenetics;
Humans;
Pediatrics;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Precursor Cells, B-Lymphoid;
Prognosis;
Trisomy
- From:Clinical Pediatric Hematology-Oncology
2019;26(2):91-94
- CountryRepublic of Korea
- Language:English
-
Abstract:
We present a case of Korean pediatric patient with pre-B cell type acute lymphoblastic leukemia (ALL) with trisomy 5 as a sole cytogenetic anomaly. Here, we compare and describe the present case with previous pediatric case reports and provide a review of the literature. This case report may help elucidate the poor prognostic impact of trisomy 5 as a sole cytogenetic anomaly in pediatric patients with ALL. Additional studies are needed to confirm this hypothesis.