New Diagnostic Approach for Esophageal Squamous Cell Neoplasms Using Linked Color Imaging and Blue Laser Imaging Combined with Iodine Staining
- Author:
Masato TSUNODA
1
;
Yoshimasa MIURA
;
Hiroyuki OSAWA
;
Tsevelnorov KHURELBAATAR
;
Mio SAKAGUCHI
;
Hisashi FUKUDA
;
Alan Kawarai LEFOR
;
Hironori YAMAMOTO
Author Information
- Publication Type:Case Report
- Keywords: Early esophageal cancer; Image enhanced endoscopy; Linked color imaging; Blue laser imaging; Iodine staining
- MeSH: Carcinoma, Squamous Cell; Epithelial Cells; Esophageal Neoplasms; Humans; Iodine; Methods; Middle Aged; Neoplasms, Squamous Cell
- From:Clinical Endoscopy 2019;52(5):497-501
- CountryRepublic of Korea
- Language:English
- Abstract: A 62-year-old man with a flat early esophageal cancer was referred for endoscopic treatment. White light imaging revealed a pale red lesion, whereas linked color imaging (LCI) and blue laser imaging (BLI) yielded purple and brown images, respectively. Iodine staining demonstrated a large unstained area with a homogenous but very weak pink-color sign. This area appeared more clearly as purple and green on LCI and BLI, respectively; however, a different colored portion was observed at the 4 o'clock position inside the iodine-unstained area. Histopathology findings of the resected specimen revealed squamous intraepithelial neoplasia at the 4 o'clock position and an esophageal squamous cell carcinoma in the remaining iodine-unstained area. LCI and BLI combined with iodine staining produce characteristic images that overcomes the pink-color sign, reflecting the histological features of a flat esophageal neoplasm. This new method is useful for detailed evaluation of early flat squamous cell neoplasms.
