Effects of different exercise modalities on novel hepatic steatosis indices in overweight women with type 2 diabetes
- Author:
Ebrahim BANITALEBI
1
;
Mohammad FARAMARZI
;
Samira NASIRI
;
Majid MARDANIYAN
;
Vahid RABIEE
Author Information
- Publication Type:Original Article
- Keywords: High-intensity interval training; Non-alcoholic fatty liver disease; Diabetes mellitus, Type 2
- MeSH: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Fatty Liver; Female; Humans; Lipid Accumulation Product; Liver; Non-alcoholic Fatty Liver Disease; Overweight
- From:Clinical and Molecular Hepatology 2019;25(3):294-304
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Fatty liver is a clinical and pathologic condition in individuals with type 2 diabetes (T2D). The purpose of this study is to examine the effects of different exercise modalities on non-alcoholic fatty liver indices (fatty liver index [FLI], lipid accumulation product [LAP], hepatic steatosis index [HSI], and Framingham Steatosis Index [FSI]) in women with T2D. METHODS: Fifty-two women with T2D and a mean age of 55.07±5.92 yrs, body mass index (BMI) 28.94±4.09 kg/m² , and hemoglobin A1c (HbA1c) 9.41±0.82% were randomized to a sprint interval training (SIT) (n=17), combined aerobic and resistance (A+R) training (n=17), or control group (n=18) for 10 weeks. Two-way repeated analysis of variance (ANOVA) was used to find differences between groups and the effects of time and Time×Group interactions after 10 weeks on non-alcoholic fatty liver indices. After this, ANOVA models were constructed to determine the effects of group allocation and change in non-alcoholic fatty liver indices. RESULTS: There were significant time interactions for FLI (P<0.001), HSI (P<0.001), and LAP (P<0.001). Also, there were significant Time×Group interactions for fasting blood glucose (P=0.034), and HbA1c (P=0.006). CONCLUSIONS: Results highlight that exercise training, independent of mode of training, is an effective strategy to improve some indices related to hepatic steatosis and blood glucose profiles in women with T2D.
