Long-term Breastfeeding in the Prevention of Allergic Rhinitis: Allergic Rhinitis Cohort Study for Kids (ARCO-Kids Study)
- Author:
Doo Hee HAN
1
;
Jae Min SHIN
;
Seokyung AN
;
Jong Seung KIM
;
Dong Young KIM
;
Sungji MOON
;
Jung Soo KIM
;
Joong Saeng CHO
;
Si Whan KIM
;
Young Hyo KIM
;
Hwan Jung ROH
;
Woo Sub SHIM
;
Ki Sang RHA
;
Sang Wook KIM
;
Seung Sin LEE
;
Dae Woo KIM
;
Kyu Sup CHO
;
Hyo Jin YIM
;
Sue K PARK
;
Chae Seo RHEE
Author Information
- Publication Type:Original Article
- Keywords: Rhinitis, Allergic; Breast Feeding; Environment; Delivery, Obstetric; Cesarean Section
- MeSH: Breast Feeding; Cesarean Section; Child; Cohort Studies; Delivery, Obstetric; Female; Humans; Odds Ratio; Pregnancy; Prevalence; Rhinitis; Rhinitis, Allergic
- From:Clinical and Experimental Otorhinolaryngology 2019;12(3):301-307
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVES: There is a great deal of interest in the possibility that environmental factors may influence the risk of developing allergic rhinitis (AR) in early life. We investigated the simultaneous effects of mode of delivery and duration of breastfeeding on the development of AR in children. METHODS: Data from 1,374 children participating in the Allergic Rhinitis Cohort Study for kids (ARCO-kids study) was analyzed. All subjects were divided into AR or non-allergic rhinitis (NAR) groups. Data on environmental factors, mode of delivery and duration of breastfeeding were collected using a questionnaire. RESULTS: Compared with short-term breastfeeding (<6 months), long-term breastfeeding (≥12 months) was significantly associated with a lower prevalence of AR (adjusted odds ratio [aOR], 0.54; 95% confidence interval [CI], 0.34 to 0.88). Children in the AR group also had a higher cesarean delivery rate than those in the NAR group (39.1% vs. 32.8%, P=0.05). Regarding the combined effects of mode of delivery and duration of breastfeeding, long-term breastfeeding with a vaginal delivery strongly suppressed the development of AR, compared to short-term breastfeeding with a cesarean delivery (aOR, 0.47; 95% CI, 0.30 to 0.73). CONCLUSION: Long-term breastfeeding (≥12 months) and a vaginal delivery are associated with a lower risk of developing childhood AR.
