Recent Advances in Biosensors for Nucleic Acid and Exosome Detection
- Author:
Zirui FU
1
;
Yi Cheng LU
;
James J LAI
Author Information
- Publication Type:Review
- Keywords: Biosensing Techniques; Optical Biosensors; Electrochemical Biosensors; Exosomes; Nucleic Acids
- MeSH: Biosensing Techniques; Exosomes; Food Industry; In Vitro Techniques; Nucleic Acids; Signal Transduction; Transducers
- From:Chonnam Medical Journal 2019;55(2):86-98
- CountryRepublic of Korea
- Language:English
- Abstract: Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied in diverse fields such as clinical monitoring, in vitro diagnostics, food industry etc. Based on signal transduction mechanisms, biosensors can be categorized into three major types: optical biosensors, electrochemical biosensors, and mass-based biosensors. Recently, the need for faster, more sensitive detection of biomolecules has compeled researchers to develop various sensing techniques. In this review, the basic structure and sensing principles of biosensors are introduced. Additionally, the review discusses multiple recent works about nucleic acid and exosome sensing.
