A Case of Primary Central Nervous System Vasculitis That Worsened Despite Early Corticosteroid Therapy

Author: Sang Youl YOON ¹ ; Ki Su PARK ; Seong Hyun PARK ; Ji Young PARK
Author Information

1. Department of Neurosurgery, Kyungpook National University School of Medicine, Kyungpook National University Hospital, Daegu, Korea. kiss798@gmail.com
Publication Type:Case Report
Keywords: Vasculitis; Cysts; Neoplasms; Glucocorticoids
MeSH: Adrenal Cortex Hormones; Craniotomy; Cyclophosphamide; Diagnosis; Edema; Frontal Lobe; Glucocorticoids; Humans; Middle Aged; Vasculitis; Vasculitis, Central Nervous System
From:Brain Tumor Research and Treatment 2019;7(2):164-167
CountryRepublic of Korea
Language:English
Abstract: Primary central nervous system vasculitis (PCNSV) is rare, and the diagnosis is difficult to make because of its variable radiologic expressions. Early corticosteroid therapy often is effective. Herein we report the case of a 56-year-old man who had a well-enhanced cystic mass with severe edema in the right frontal lobe, which was initially felt to be a malignancy. Histologic examination of tissue removed at craniotomy revealed that it was a PCNSV. Despite early administration of corticosteroids, a new lesion developed within 3 days. The lesions responded to treatment with cyclophosphamide and corticosteroid.