Practicality and importance of selected endothelial dysfunction measurement techniques: review
10.1007/s13534-018-0089-9
- Author:
Michael D WHITT
1
;
Mark J JACKSON
Author Information
1. College of Engineering, California Polytechnic State University, San Luis Obispo, CA 93407, USA. mdwhitt@calpoly.edu
- Publication Type:Review
- Keywords:
Measurement;
Endothelial dysfunction;
Medical physics
- MeSH:
Cardiovascular Diseases;
Coronary Artery Disease;
Humans;
Methods
- From:
Biomedical Engineering Letters
2019;9(1):87-95
- CountryRepublic of Korea
- Language:English
-
Abstract:
The measurement of endothelial dysfunction (ED) has importance in that it indicates the presence of coronary artery disease (Kuvin et al. in J Am Coll Cardiol 38(7):1843–1849, 2001) in addition to acting as a predictor of future adverse events (Halcox et al. in Circulation 106:653–658, 2002). Various tools, methods, and metrics exist that can provide an indicator of endothelial dysfunction. Given the signifi cance of ED, it is of utmost importance to fi nd a measurement technique that is reliable, while defi ning a metric providing a framework for an overall system that is practical, accurate, and repeatable. Success would provide a tool for the early detection of cardiovascular disease not only moving patients that are currently classifi ed as asymptomatic to symptomatic, but also providing a method to monitor the effi cacy of treatments.
