A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection
10.6065/apem.2019.24.1.68
- Author:
Hüseyin Anıl KORKMAZ
1
;
Cağatay ERMIŞ
Author Information
1. Division of of Pediatric Endocrinology, Balıkesir Atatürk State Hospital, Balıkesir, Turkey. hanilkorkmaz@gmail.com
- Publication Type:Case Report
- Keywords:
Rubella;
Diabetes;
Hearing loss
- MeSH:
Adolescent;
Autoantibodies;
Cataract;
Diabetes Mellitus;
Diabetes Mellitus, Type 1;
Ductus Arteriosus, Patent;
Fetal Growth Retardation;
Glucose Tolerance Test;
Hearing Loss;
Humans;
Male;
Microcephaly;
Polydipsia;
Polyuria;
Rubella;
Thrombocytopenia;
Urination;
Weight Loss
- From:Annals of Pediatric Endocrinology & Metabolism
2019;24(1):68-70
- CountryRepublic of Korea
- Language:English
-
Abstract:
Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.
