The effect of shift work on high sensitivity C-reactive protein level among female workers
- Author:
Ho Sung KWAK
1
;
Hyoung Ouk PARK
;
Young Ouk KIM
;
Jun Seok SON
;
Chan Woo KIM
;
Jun Ho LEE
;
Young Hoo SHIN
;
Seung Hyun PARK
;
Eui Yup CHUNG
;
Chang Ho CHAE
Author Information
- Publication Type:Original Article
- Keywords: Shift work; Inflammation; High sensitivity C-reactive protein; Female workers
- MeSH: Alcohol Drinking; Appointments and Schedules; C-Reactive Protein; Cardiovascular Diseases; Depression; Education; Female; Follow-Up Studies; Hematologic Tests; Humans; Inflammation; Korea; Marital Status; Risk Factors; Smoke; Smoking
- From:Annals of Occupational and Environmental Medicine 2019;31(1):e5-
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: This study assessed the association between shift work and high-sensitivity C-reactive protein (hs-CRP) level, a risk factor for cardiovascular disease (CVD), in female workers in electronics manufacturing services (EMS). METHODS: Female EMS workers who received special medical examinations for workers in Gyeongnam, Korea between January 2017 and December 2017 were enrolled in this study. Their age, marital status, education level, alcohol consumption, smoking habit, regular exercise, quality of sleep, work stress, and depression were investigated, and blood tests were conducted. The t- and χ2 tests were conducted to compare the general and biochemical characteristics between daytime and shift worker groups. Age-adjusted partial correlation analysis was performed to examine the linear relationship between hs-CRP level and other risk factors for CVDs. In addition, the difference in hs-CRP levels according to work schedule was analyzed by ANCOVA after adjusting for variables that could affect the hs-CRP level. RESULTS: Although the average hs-CRP levels did not differ significantly between daytime and shift workers (0.92 ± 1.87 and 1.07 ± 2.20 mg/dL, respectively), shift workers tended to show a higher hs-CRP level (p = 0.067). After adjusting for variables that can affect the hs-CRP level, the estimated average hs-CRP level was significantly higher in shift workers (1.325 ± 0.156 mg/dL) than that in daytime workers (0.652 ± 0.350 mg/dL) (p = 0.003). CONCLUSIONS: The results of this study identified a relationship between shift work and hs-CRP level increase in women. Because multiple studies have reported associations between increased hs-CRP and CVD, follow-up of hs-CRP may help early detection of CVD in shift workers.
