Treatment of Hidradenitis Suppurativa Patient with Klinefelter Syndrome by Adalimumab
- Author:
Ji Yeoun SHIN
1
;
Jung Yeon HONG
;
Ho Jung LEE
;
Chang Yoon SIM
;
Young Lip PARK
;
Jong Suk LEE
;
Sung Yul LEE
;
Jung Eun KIM
Author Information
- Publication Type:Case Report
- Keywords: Hidradenitis suppurativa; Klinefelter syndrome
- MeSH: Adalimumab; Autoimmune Diseases; Chromosome Disorders; Comorbidity; Hidradenitis Suppurativa; Hidradenitis; Humans; Karyotype; Klinefelter Syndrome; Male; Sex Differentiation; Skin Diseases; Tumor Necrosis Factor-alpha
- From:Annals of Dermatology 2019;31(4):446-449
- CountryRepublic of Korea
- Language:English
- Abstract: Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an increased risk of metabolic disorders such as diabetes, metabolic syndrome and autoimmune diseases. Klinefelter syndrome (KS) is a sex chromosomal disorder occurring in males due to an abnormality of sexual differentiation, characterized by 47, XXY karyotype. Also, KS is related with somatic comorbidities such as metabolic syndrome, autoimmune and rheumatologic disorders as HS is. We report a HS patient with KS who shows a big improvement while on tumor necrosis factor-alpha inhibitor treatment.
