Multiple epidural fibrin glue patches in a patient with spontaneous intracranial hypotension:A case report
10.17085/apm.2019.14.3.335
- Author:
Yun Gu LEE
1
;
Mijung SA
;
In su OH
;
Jeong Ae LIM
;
Nam Sik WOO
;
Jae hun KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine, Seoul, Korea. painfree@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Epidural blood patch;
Fibrin tissue adhesive;
Headache;
Intracranial hypotension
- MeSH:
Adhesives;
Adult;
Blood Patch, Epidural;
Cerebrospinal Fluid;
Female;
Fibrin Tissue Adhesive;
Fibrin;
Headache;
Humans;
Intracranial Hypotension
- From:Anesthesia and Pain Medicine
2019;14(3):335-340
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Spontaneous intracranial hypotension (SIH) is a condition caused by spontaneous leakage of cerebrospinal fluid, with postural headache as the primary symptom. Orthostatic headache caused by SIH is often not resolved by conservative management. CASE: We performed 15 epidural blood patch treatments in a 43-year-old female patient; however, they were only transiently effective. To improve the patient's SIH and orthostatic headache, epidural fibrin glue patch treatment was attempted. Fibrin glue is a substance that can act as a bio-friendly adhesive by facilitating the coagulation cascade. In our case, 3 epidural fibrin glue patch treatments were performed and the symptoms completely resolved. CONCLUSIONS: The epidural fibrin glue patch may be beneficial for the treatment of refractory postural headaches caused by SIH.