The potential risks of sugammadex
10.17085/apm.2019.14.2.117
- Author:
Wonjin LEE
1
Author Information
1. Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, Busan, Korea. 2wonjin@naver.com
- Publication Type:Review
- Keywords:
Adverse effects;
Blood coagulation disorders;
Bradycardia;
Drug interactions;
Neurotoxicity syndromes;
Sugammadex
- MeSH:
Blood Coagulation Disorders;
Bradycardia;
Drug Interactions;
Neuromuscular Blockade;
Neurons;
Neurotoxicity Syndromes;
Steroids
- From:Anesthesia and Pain Medicine
2019;14(2):117-122
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sugammadex provides fast and safe recovery from neuromuscular blockade without causing major adverse effects, and its clinical use is increasing. However, there are some reports on the potential risks of sugammadex, such as severe bradycardia, interactions with steroids, coagulopathy, and neuronal damage. Although these potential risks are not clearly proven, they are considered to be dose-dependent and occur more frequently with the free-form of sugammadex. Until further pieces of evidence are accumulated, it is prudent to be aware of these potential risks and avoid an overdose of sugammadex.
