Associated Factors for Asthma Severity in Korean Children: A Korean Childhood Asthma Study
10.4168/aair.2020.12.1.86
- Author:
Eun LEE
1
;
Dae Jin SONG
;
Woo Kyung KIM
;
Dong In SUH
;
Hey Sung BAEK
;
Meeyong SHIN
;
Young YOO
;
Jin Tack KIM
;
Ji Won KWON
;
Gwang Cheon JANG
;
Dae Hyun LIM
;
Hyeon Jong YANG
;
Hwan Soo KIM
;
Ju Hee SEO
;
Sung Il WOO
;
Hyung Young KIM
;
Youn Ho SHIN
;
Ju Suk LEE
;
Jisun YOON
;
Sungsu JUNG
;
Minkyu HAN
;
Eunjin EOM
;
Jinho YU
Author Information
1. Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
- Publication Type:Original Article
- Keywords:
Child;
asthma;
severity;
risk factor;
environmental exposure;
smoke;
dogs;
education status;
air pollution
- MeSH:
Air Filters;
Air Pollution;
Animals;
Asthma;
Child;
Dander;
Dogs;
Education;
Environmental Exposure;
Humans;
Logistic Models;
Odds Ratio;
Ownership;
Risk Factors;
Smoke;
Social Change;
Tobacco
- From:Allergy, Asthma & Immunology Research
2020;12(1):86-98
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Childhood asthma has a considerable social impact and economic burden, especially in severe asthma. This study aimed to identify the proportion of childhood asthma severity and to evaluate associated factors for greater asthma severity. METHODS: This study was performed on 667 children aged 5–15 years with asthma from the nationwide 19 hospitals in the Korean childhood Asthma Study (KAS). Asthma was classified as mild intermittent, mild persistent, and moderate/severe persistent groups according to the National Asthma Education and Prevention Program recommendations. Multinomial logistic regression models were used to identify the associated factors for greater asthma severity. RESULTS: Mild persistent asthma was most prevalent (39.0%), followed by mild intermittent (37.6%), moderate persistent (22.8%), and severe persistent asthma (0.6%). Onset later than 6 years of age (adjusted odds ratio [aOR], 1.69 for mild persistent asthma; aOR, 1.92 for moderate/severe persistent asthma) tended to increase asthma severity. Exposure to environmental tobacco smoke (aOR, 1.53 for mild persistent asthma; aOR, 1.85 for moderate/severe persistent asthma), and current dog ownership with sensitization to dog dander (aOR, 5.86 for mild persistent asthma; aOR, 6.90 for moderate/severe persistent asthma) showed increasing trends with greater asthma severity. Lower maternal education levels (aOR, 2.32) and no usage of an air purifier in exposure to high levels of outdoor air pollution (aOR, 1.76) were associated with moderate/severe persistent asthma. CONCLUSIONS: Modification of identified environmental factors associated with greater asthma severity might help better control childhood asthma, thereby reducing the disease burden due to childhood asthma.
