Carriage prevalence and susceptibility to penicillin of streptococcus pneumonia isolated from healthy children under 5 years old
- Author:
Trung Vu Nguyen
;
Quyen Huu Nguyen
- Publication Type:Journal Article
- Keywords:
Prevalence;
Streptococcus pneumonia;
Penicillin
- MeSH:
Prevalence;
Streptococcus pneumonia;
Penicillin
- From:Journal of Medical Research
2008;58(5):34-39
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: S.pneumoniae is a significant cause of respiratory tract infections in children under 5 years old. More strains of S.pneumoniae show less susceptibility to penicillin, and antibiotic commonly used in the treatment of pneumococcal infections. Objectives: To identify the carriage prevalence and susceptibility to penicillin of S.pneumonia isolated from children under 5 years old. Subject and Method: The study included 823 children under 5 years old living in Ba Vi, Ha Tay. Culture, bacterial identification and antibiogram by E- test have been applied in this study. Results: 51.4% of nasopharyngeal samples had S.pneumoniae. The prevalence of S.pneumoniae isolated resistant and intermediate to penicillin were 15.5% and 64%, respectively. Resistance prevalence of streptococcal isolates in children older and younger than 2 years of age were 14.1% and 17.3%, respectively. Conclusion: Approximately 80% of S.pneumoniae was non-susceptible to penicillin. There is an immense requirement to monitor the antibiotic susceptibility of S. pneumonia and to have prompt recommendations for treatment.
