Gastroparesis: Current Concepts and Management.
- Author:
Tatsuhiro MASAOKA
1
;
Jan TACK
Author Information
1. Center for Gastroenterological Research, University of Leuven, Leuven, Belgium. jan.tack@med.kuleuven.be
- Publication Type:Review
- Keywords:
Gastroparesis;
Diabetes mellitus;
Delayed gastric emptying;
Prokinetic therapy;
Gastric electrical stimulation
- MeSH:
Botulinum Toxins;
Diabetes Mellitus;
Domperidone;
Electric Stimulation;
Gastrectomy;
Gastric Emptying;
Gastroparesis;
Humans;
Jejunostomy;
Metoclopramide;
Nausea;
Vomiting;
Weight Loss
- From:Gut and Liver
2009;3(3):166-173
- CountryRepublic of Korea
- Language:English
-
Abstract:
Delayed gastric emptying in the absence of mechanical obstruction is referred to as gastroparesis. Symptoms that are often attributed to gastroparesis include postprandial fullness, nausea, and vomiting. Although tests of gastric motor function may aid diagnostic labeling, their contribution to determining the treatment approach is often limited. Although clinical suspicion of gastroparesis warrants the exclusion of mechanical causes and serum electrolyte imbalances, followed by empirical treatment with a gastroprokinetic such as domperidone or metoclopramide, evidence that these drugs are effective for patients with gastroparesis is far from overwhelming. In refractory cases with severe weight loss, invasive therapeutics such as inserting a feeding jejunostomy tube, intrapyloric injection of botulinum toxin, surgical (partial) gastrectomy, and implantable gastric electrical stimulation are occasionally considered.
