Matrix Production in Chondrocytes Transfected with Sex Determining Region Y-Box 9 and Telomerase Reverse Transcriptase Genes: An In Vitro Evaluation from Monolayer Culture to Three-Dimensional Culture
10.1007/s13770-019-00191-1
- Author:
Md Nazir NOORHIDAYAH
1
;
Ahmad Hafiz ZULKIFLY
;
Kamarul Ariffin KHALID
;
Ismail ZAINOL
;
Zaitunnatakhin ZAMLI
;
Munirah SHA'BAN
Author Information
1. Department of Biomedical Science, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Darul Makmur, Malaysia.
- Publication Type:Original Article
- Keywords:
Cartilage;
Chondrocytes;
Glycosaminoglycan;
Proteoglycan;
Tissue engineering
- MeSH:
Alcian Blue;
Cartilage;
Chondrocytes;
Clothing;
Coloring Agents;
Eosine Yellowish-(YS);
In Vitro Techniques;
Proteoglycans;
Real-Time Polymerase Chain Reaction;
Regeneration;
Telomerase;
Tissue Engineering;
Transfection
- From:
Tissue Engineering and Regenerative Medicine
2019;16(3):285-299
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: This study aimed to observe the cartilaginous matrix production in SRY (sex determining region Y)-box 9 (SOX9)- and/or telomerase reverse transcriptase (TERT)-transfected chondrocytes from monolayer to three-dimensional (3D) culture.