Neurocysticercosis: Clinical Characteristics and Changes from 26 Years of Experience in an University Hospital in Korea
10.3347/kjp.2019.57.3.265
- Author:
Hyo Ju SON
1
;
Min Jae KIM
;
Kyung Hwa JUNG
;
Sungim CHOI
;
Jiwon JUNG
;
Yong Pil CHONG
;
Sung Han KIM
;
Sang Oh LEE
;
Sang Ho CHOI
;
Yang Soo KIM
;
Jun Hee WOO
;
Bong Kwang JUNG
;
Hyemi SONG
;
Jong Yil CHAI
Author Information
1. Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. nahani99@gmail.com
- Publication Type:Original Article
- Keywords:
Taenia solium;
neurocysticercosis;
human taeniasis;
Korea
- MeSH:
Chungcheongnam-do;
Headache;
Humans;
Hydrocephalus;
Korea;
Male;
Neurocysticercosis;
Neuroimaging;
Ovum;
Pathology;
Prevalence;
Retrospective Studies;
Seizures;
Taenia solium;
Taeniasis;
Tertiary Care Centers;
Ventriculoperitoneal Shunt
- From:The Korean Journal of Parasitology
2019;57(3):265-271
- CountryRepublic of Korea
- Language:English
-
Abstract:
The prevalence of human taeniasis has decreased in Korea. The stool egg positive proportion decreased from 1.9% in 1971 to 0% in 2004 in nationwide surveys. The neurocysticercosis (NCC) is also presumed to decrease. However, detailed information regarding the recent status of NCC in Korea is lacking. We retrospectively reviewed NCC cases from 1990 to 2016 at Asan Medical Center, a 2700-bed tertiary referral hospital in Korea. We identified patients based on clinical symptoms, brain imaging, pathology and serological assay. The cases were classified as parenchymal, extraparenchymal, and mixed NCC. Eighty-one patients were included in the analysis. The mean age was 54.5 years, and 79.0% were male. The number of NCC cases was highest from 1995 to 1999, and continuously decreased thereafter. Forty (49.4%) patients had parenchymal NCC, while 25 (30.9%) patients had extraparenchymal NCC, and 16 (19.8%) patients had mixed NCC. The seizure and headache were most common symptom of parenchymal NCC and extraparenchymal NCC respectively. Hydrocephalus was more common in extraparenchymal NCC, and patients with extraparenchymal NCC were more likely to require a ventriculoperitoneal shunt. Cases of NCC are decreasing accordingly with human taeniasis and lesion location was the most important determinant of clinical presentation and outcome of NCC in Korea.
