Current Status of Primary Glomerulonephritis.
- Author:
Dong Wan CHAE
1
Author Information
1. Division of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. cdw1302@snubh.org
- Publication Type:Review
- Keywords:
Korea;
Glomerulonephritis;
Manifestations elderly;
ESRD
- MeSH:
Aged;
Biopsy;
Corneal Dystrophies, Hereditary;
Dialysis;
Glomerulonephritis;
Glomerulonephritis, IGA;
Glomerulonephritis, Membranous;
Glomerulosclerosis, Focal Segmental;
Humans;
Kidney Failure, Chronic;
Korea;
Nephrosis, Lipoid;
Nephrotic Syndrome;
Prevalence;
Proteinuria
- From:Korean Journal of Medicine
2013;84(1):1-5
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recent change in major indication for renal biopsy from nephrotic syndrome to asymptomatic urinary abnormality (AU) in Korea makes IgA nephropathy the most common biopsy-confirmed glomerulonephritis (GN). Beside from the most common manifestation of AU, a significant portion (22%) of IgA nephropathy (IgAN) patient revealed the nephrotic-range proteinuria. About 1/3 of patients with minimal change disease (MCD), membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS) presented with AU. In elderly patient (> 60 years), the proportion of cresentic glomerulonephritis, MN, and FSGS increased, while the prevalence of IgAN decreased compared to younger patients. MCD showed no change based on old age. GN was the third most common cause of ESRD constituting 11-15% of cases. ESRD patients from GN start dialysis younger and live longer on dialysis compared to diabetic and hypertensive patients in Korea.
