Hepatitis E Virus: Epidemiology, Diagnosis, and Management
10.4166/kjg.2019.74.3.130
- Author:
Nae Yun HEO
1
Author Information
1. Division of Gastroenterology, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. nyheo@hanmail.net
- Publication Type:Review
- Keywords:
Hepatitis E;
Waterborne diseases;
Zoonoses;
Genotype
- MeSH:
Developing Countries;
Diagnosis;
Disease Outbreaks;
Female;
Genotype;
Hand;
Hepatitis E virus;
Hepatitis E;
Hepatitis;
Hepatitis, Chronic;
Humans;
Liver Cirrhosis;
Male;
Mortality;
Pregnant Women;
Swine;
Transplants;
Waterborne Diseases;
Zoonoses
- From:The Korean Journal of Gastroenterology
2019;74(3):130-136
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The HEV is a known cause of water-borne outbreaks of acute non-A non-B hepatitis in developing countries, which affects young people and may result in high mortality in pregnant women. In recent decades, however, HEV genotypes 3 and 4 have been known as a cause of sporadic zoonotic infections in older males from swine HEV worldwide. Most acute HEV infections are self-limited. On the other hand, in immunosuppressed patients, including solid organ transplant recipients, chronic HEV infections may exist and progress to liver cirrhosis or decompensation. Therefore, physicians need to recognize HEV as a major pathogen for acute and chronic hepatitis of unknown causes and investigate this disease.
