Two Cases of Radiologically Isolated Syndrome: First Case Report in Korea
- Author:
Kayeong IM
1
;
Jun Sang SUNWOO
;
Kyum Yil KWON
;
Kyung Bok LEE
;
Moo Young AHN
;
Hakjae ROH
Author Information
1. Department of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University of College of Medicine, Seoul, Korea. newroh@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Magnetic resonance imaging;
Multiple sclerosis;
Demyelinating diseases
- MeSH:
Demyelinating Diseases;
Humans;
Incidence;
Korea;
Magnetic Resonance Imaging;
Multiple Sclerosis;
Natural History;
Neurologic Manifestations;
Prevalence;
Prognosis;
White Matter
- From:Soonchunhyang Medical Science
2019;25(1):65-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
With increasing sensitivity, availability, and use of magnetic resonance imaging (MRI) in the past three decades, there is also an increase in incidental abnormal findings. The most common findings of these incidental abnormalities are white matter lesions that are interpreted as demyelinating based on radiological criteria. MRI findings suggestive of multiple sclerosis (MS) in patients without typical MS symptoms and with normal neurologic findings are now defined as a radiologically isolated syndrome (RIS) which reported relatively low incidence, especially hard to find case report in Korea. The natural history and pathophysiologic processes of RIS remain largely unknown. The nature, prevalence, and long-term prognosis of RIS, as well as the role of disease-modifying therapy should be established in the future.
