Brain Hypometabolism in Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome
10.21790/rvs.2017.16.4.156
- Author:
Byoung Min JEONG
1
;
Byoung Soo SHIN
;
Man Wook SEO
;
Ji Yun PARK
;
Hwan Jeong JEONG
;
Sun Young OH
Author Information
1. Department of Neurology, Chonbuk National University Medical School, Jeonju, Korea. ohsun@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Bilateral vestibulopathy;
Cerebellar ataxia;
Primary dysautonomias;
Positron-emission tomography
- MeSH:
Atrophy;
Brain;
Cerebellar Ataxia;
Cerebellum;
Diagnosis;
Gyrus Cinguli;
Humans;
Neuroimaging;
Positron-Emission Tomography;
Primary Dysautonomias;
Thalamus;
Vestibular Neuronitis
- From:Journal of the Korean Balance Society
2017;16(4):156-160
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a slowing progressive ataxic disorder characterized by bilateral vestibulopathy, cerebellar ataxia and somatosensory impairment. Autonomic dysfunction is recently considered as a core feature in CANVAS in addition to these symptoms. In most cases, patients with CANVAS show cerebellar atrophy in brain imaging, but some cases show minimal or no atrophy of cerebellum. Brain (18F)-fluoro-2-deoxy-D-glucose positron emission tomography (¹⁸F-FDG PET) study can be a complimentary tool to diagnosis CANVAS in cases of no structural abnormality such as cerebellar atrophy. Hereby, we present a case of CANVAS with minimal atrophy of cerebellum but showing a prominent hypometabolism in cerebellum, thalamus and posterior cingulate cortex in ¹⁸F-FDG PET.
