Interfraction variation and dosimetric changes during image-guided radiation therapy in prostate cancer patients
- Author:
Frederik FUCHS
1
;
Gregor HABL
;
Michal DEVEČKA
;
Severin KAMPFER
;
Stephanie E COMBS
;
Kerstin A KESSEL
Author Information
- Publication Type:Original Article
- Keywords: Prostatic neoplasms; Image-guided radiotherapy; Intensity-modulated radiotherapy; Urinary bladder; Rectum
- MeSH: Humans; Organs at Risk; Prostate; Prostatic Neoplasms; Radiotherapy, Image-Guided; Radiotherapy, Intensity-Modulated; Rectum; Urinary Bladder
- From:Radiation Oncology Journal 2019;37(2):127-133
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: The aim of this study was to identify volume changes and dose variations of rectum and bladder during radiation therapy in prostate cancer (PC) patients. MATERIALS AND METHODS: We analyzed 20 patients with PC treated with helical tomotherapy. Daily image guidance was performed. We re-contoured the entire bladder and rectum including its contents as well as the organ walls on megavoltage computed tomography once a week. Dose variations were analyzed by means of Dmedian, Dmean, Dmax, V₁₀ to V₇₅, as well as the organs at risk (OAR) volume. Further, we investigated the correlation between volume changes and changes in Dmean of OAR.
