A Systematic Review and Meta-Analysis of Nonpharmacological Interventions for Moderate to Severe Dementia
- Author:
Riyoung NA
1
;
Ji Hye YANG
;
Yusung YEOM
;
You Joung KIM
;
Seonjeong BYUN
;
Kiwon KIM
;
Ki Woong KIM
Author Information
- Publication Type:Meta-Analysis
- Keywords: Dementia; Nonpharmacological intervention; Activities of daily living; Depression; Behavioral and psychological symptoms of dementia
- MeSH: Activities of Daily Living; Anxiety; Cognition; Dementia; Depression; Dihydroergotamine; Methods; Music Therapy; Quality of Life
- From:Psychiatry Investigation 2019;16(5):325-335
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: Due to limited efficacy of medications, non-pharmacological interventions (NPI) are frequently co-administered to people with moderate to severe dementia (PWMSD). This systematic review and meta-analysis investigated the effects of NPI on activities of daily living (ADL), behavioral and psychological symptoms of dementia (BPSD), and cognition and quality of life (QoL) of PWMSD. METHODS: A literature search was conducted in the following databases: Cochrane CENTRAL, EMBASE, Medline, CIHNAL, PsycINFO, KoreaMED, KMbase, and KISS. We conducted a meta-analysis on randomized controlled trials and used the generic inverse variance method with a fixed-effects model to calculate the standardized mean difference (SMD). The protocol had been registered (CRD42017058020).
