Intraventricular Vancomycin Therapy for Intractable Bacillus cereus Ventriculitis

Author: Jong Woo HAHN ¹ ; Hee young JU ; Meerim PARK ; Eun Sang YI ; Byung Kiu PARK ; Sang Hoon SHIN ; Sang Hyun LEE ; Hyeon Jin PARK ; Ji Man KANG
Author Information

1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, the Republic of Korea.
Publication Type:Case Report
Keywords: Bacillus cereus; Injections, intraventricular; Central nervous system infection; Vancomycin; Pharmacokinetics; Cerebral ventriculitis
MeSH: Bacillus cereus; Bacillus; Central Nervous System Infections; Cerebral Ventriculitis; Cerebrospinal Fluid; Immunocompromised Host; Injections, Intraventricular; Pharmacokinetics; Vancomycin
From:Pediatric Infection & Vaccine 2019;26(2):124-128
CountryRepublic of Korea
Language:English
Abstract: Bacillus cereus causes serious central nervous system infections, especially in immunocompromised patients. Successful treatment requires adequate antimicrobial concentrations in the cerebrospinal fluid; however, in some cases, achieving this with systemic treatment alone is difficult. We treated intractable B. cereus ventriculitis with intraventricular vancomycin, with no major adverse events.