Influence of Oral and Intravenous Bisphosphonate for the Patients Treated Surgically in Osteoporotic Distal Radius Fracture
- Author:
Joong Bae SEO
1
;
Jong Pil KIM
;
Ki Choul KIM
;
Changhwan HWANG
;
Seokwon YANG
;
Jae Sung YOO
Author Information
1. Department of Orthopedic Surgery, Dankook University College of Medicine, Cheonan, Korea. idbabe@naver.com
- Publication Type:Original Article
- Keywords:
Distal radius;
Distal radius fracture;
Osteoporosis;
Bisphosphonate
- MeSH:
Humans;
Medical Records;
Osteoporosis;
Radius Fractures;
Radius;
Range of Motion, Articular;
Retrospective Studies;
Wrist
- From:Journal of Korean Society of Osteoporosis
2013;11(2):89-95
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Purpose of this study is investigation the influence of intravenous and oral bisphosphonate to bone union and clinical results in patient treated with plate fixation in an osteoporotic distal radius fracture. MATERIALS AND METHODS: The medical records of 160 patients with an osteoporotic distal radius fracture treated with plate fixation in our hospital between January 2008 and April 2012 were reviewed retrospectively. The patients were classified by 3 groups; who did not administrate bisphosphonate after surgery as Group I (n=69), administrated oral bisphosphonate after surgery as Group II (n=44), and administrated intravenous bisphosphonate as Group III (n=47). After surgery, bone union, radiologic parameters, disabilities of the DASH score and range of motion of wrist were assessed. RESULTS: Mean time of bone union was 6.7 weeks in Group I, 6.8 weeks in Group II, and 7.1 weeks in Group III. There was no significant difference between three groups (P=0.571). Bone union rate on 6weeks shows no significant differences between three groups (P=0.16). Three groups also have no significant differences in all radiologic and clinical parameters. CONCLUSION: This study shows that early initiation of oral and Intravenous bisphosphonate did not affect bone union and clinical results compared to group who did not administrate bisphosphonate result in patient treated with plate fixation in an osteoporotic distal radius fracture.
