Changes in the Microstructural and Mechanical Properties in the Medial Condyle of Human Distal Femur in Advanced Osteoarthritis
- Author:
Kwang Kyoun KIM
1
;
Myong Hyun BAEK
;
Ye Yeon WON
Author Information
1. Department of Orthopaedic Surgery, Konyang University Hospital, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Trabecular bone;
osteoarthritis;
FE-model;
Micro-CT
- MeSH:
Cadaver;
Femur;
Humans;
Osteoarthritis
- From:Journal of Korean Society of Osteoporosis
2012;10(2):61-66
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: The purpose of this study is to analyze and compare the micro-structural and mechanical properties of subchondral trabecular bone of non-osteoarthritic and osteoarthritic distal femur using micro-images based on finite element analysis. MATERIALS AND METHODS: Twenty distal femurs were harvested from 10 cadavers. The subchondral trabeculae were obtained from the middle of the articular surface of the medial femoral condyle of distal femurs. A total of 20 specimens were scanned using the micro-CT system. Micro-CT images were converted to micro-finite element model using the mesh technique, and micro-finite element analysis was then performed for assessment of the mechanical properties. RESULTS: According to the results, trabecular bone of osteoarthritic distal femur showed a decrease in trabecular thickness, bone volume fraction, structure model index, and yield stress and an increase in trabecular separation and structure model index. CONCLUSIONS: Results of bone morphometry index and strength showed greater deterioration of microstructure and decreased mechanical strength in subchondral trabeculae of the osteoarthritic group.
