A Case of Intractable Bisphosphonate-Related Osteonecrosis of the Jaw Treated with Teriparatide
- Author:
Sujin LEE
1
;
Ji Hye HUH
;
Won Jin KIM
;
Kyoung Min KIM
;
In Ho CHA
;
Yumie RHEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. YUMIE@yuhs.ac
- Publication Type:Case Report
- Keywords:
Bisphosphonate;
Bisphosphonate-related osteonecrosis of the jaw (BRONJ);
Teriparatide
- MeSH:
Bisphosphonate-Associated Osteonecrosis of the Jaw;
Diphosphonates;
Multiple Myeloma;
Osteitis Deformans;
Osteoporosis;
Teriparatide
- From:Journal of Korean Society of Osteoporosis
2012;10(2):76-81
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bisphosphonates are the most widely used medications for treating high bone turnover osteoporosis, Paget's disease of bone, multiple myeloma and metastatic carcinomas, etc. However, a destructive complication of bisphosphonate-related osteonecrosis of the jaw (BRONJ) can occur. The treatments of BRONJ are challenging and the currently recommended managements for BRONJ are still controversial. Our case demonstrated that teriparatide can be a treatment of choice for intractable BRONJ, which had not been cured for 2 years even with the proper surgical treatment and withdrawal of bisphosphonates.
