Clinical Efficacy of Korean FRAX(R) Model in Patients with Hip Fracture
- Author:
Hyung min JI
1
;
Ye Yeon WON
;
Minjung PARK
Author Information
1. Department of Orthopedic Surgery, Ajou University School of Medicine, Suwon, Korea. thrtkr@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Efficacy;
Korean FRAX model;
Patients with hip fracture
- MeSH:
Aged;
Asian Continental Ancestry Group;
Femoral Fractures;
Hip;
Hip Fractures;
Humans;
Japan;
Korea;
Osteoporosis;
Osteoporotic Fractures
- From:Journal of Korean Society of Osteoporosis
2011;9(2):170-174
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: We aimed to examine clinical efficacy of Korean FRAX model with respect to prediction of osteoporotic fracture risk and eligibility of osteoporosis treatment in Korean patients with hip fractures. MATERIALS & METHODS: In 41 elderly patients with a proximal femoral fracture (mean age=78.7 years, range: 63~99 years), fracture probabilities were calculated using FRAX models from Korea and Japan. We then performed comparative analyses between ten-year probabilities of major / hip osteoporotic fractures and the osteoporosis treatment eligibilities based on the FRAX model from Korea and Japan. RESULTS: The mean ten-year probabilities of major osteoporotic fractures and hip fractures using the Korean FRAX model (11.5% and 5.9%, respectively) were significantly lower than those using the Japanese FRAX model (21.5% and 9.2%, respectively, P<0.001). In addition, based on the National Osteoporosis Foundation guideline, pharmacological treatment of osteoporosis would be recommended in 38 patients (92.7%) by the Japanese FRAX model, while only in 30 patients (73.2%) by the Korean FRAX model (P=0.037). CONCLUSIONS: Our results suggest that the Korean FRAX model might underestimate osteoporotic fracture probabilities and eligibility of osteoporosis treatment in Korean patients with hip fracture.
