Decreased Bone Mineral density of Spine in Patients with Invasive Cervical Cancer
- Author:
Hoon CHOI
1
;
Min Hyung JUNG
;
Yong il JI
;
Hyeok JUNG
;
Ji Young LEE
;
Won Jun CHOI
;
Ari KIM
;
Jong Soon CHOI
;
Young Lim OH
;
Heung Yeol KIM
Author Information
1. Department of Obstetrics and Gynecology, School of Medicine, Sanggye Paik Hospital, Inje University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Bone mineral density;
Cervical cancer;
Osteoporosis
- MeSH:
Absorptiometry, Photon;
Bone Density;
Female;
Humans;
Osteoporosis;
Spine;
Uterine Cervical Neoplasms
- From:Journal of Korean Society of Osteoporosis
2011;9(1):46-50
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: To investigate the spinal bone mineral density (BMD) in patients with invasive cervical cancer without bone metastases. METHODS: We measured spinal bone mineral densities by dual-photon absorptiometry in 119 patients with invasive uterine cervical cancer and compared them with measurements from 135 control women. RESULTS: When adjusted for age, mean bone mineral density in patients with uterine cervical cancer was 13.9% lower (P=0.0003) and age-matched percentiles were 9.2% lower (P=0.0003) than in control women. The deficits in bone mineral density and age-matched percentiles were confined to the uterine cervical cancer patients in their fifties. CONCLUSIONS: Our study results suggest that patients with invasive cervical cancer have a lower spinal BMD, resulting in an increased risk of osteoporosis.
