A comparison of 6 osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia
10.1016/j.afos.2019.09.001
- Author:
Li Shean TOH
1
;
Pauline Siew Mei LAI
;
David Bin Chia WU
;
Brian G BELL
;
Cuu Phuong Linh DANG
;
Bee Yean LOW
;
Kok Thong WONG
;
Giuseppe GUGLIELMI
;
Claire ANDERSON
Author Information
1. Division of Pharmacy Practice and Policy, School of Pharmacy, University of Nottingham, University Park, Nottingham, UK. lishean.toh@nottingham.ac.uk
- Publication Type:Original Article
- Keywords:
Osteoporosis;
Screening;
Osteoporosis self-assessment tool for asians;
Risk assessment;
Performance comparison
- MeSH:
Absorptiometry, Photon;
Area Under Curve;
Body Weight;
Bone Diseases, Metabolic;
Estrogens;
Female;
Humans;
Malaysia;
Mass Screening;
Osteoporosis;
Risk Assessment;
Self-Assessment
- From:Osteoporosis and Sarcopenia
2019;5(3):75-81
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: To compare and assess the performance of 6 osteoporosis risk assessment tools for screening osteoporosis in Malaysian postmenopausal women. METHODS: Six osteoporosis risk assessments tools (the Simple Calculated Osteoporosis Risk Estimation [SCORE], the Osteoporosis Risk Assessment Instrument, the Age Bulk One or Never Estrogen, the body weight, the Malaysian Osteoporosis Screening Tool, and the Osteoporosis Self-Assessment Tool for Asians) were used to screen postmenopausal women who had not been previously diagnosed with osteoporosis/osteopenia. These women also underwent a dual-energy X-ray absorptiometry (DXA) scan to confirm the absence or presence of osteoporosis. RESULTS: A total of 164/224 participants were recruited (response rate, 73.2%), of which only 150/164 (91.5%) completed their DXA scan. Sixteen participants (10.7%) were found to have osteoporosis, whilst 65/150 (43.3%) were found to have osteopenia. Using precision-recall curves, the recall of the tools ranged from 0.50 to 1.00, whilst precision ranged from 0.04 to 0.14. The area under the curve (AUC) ranged from 0.027 to 0.161. The SCORE had the best balance between recall (1.00), precision (0.04–0.12), and AUC (0.072–0.161). CONCLUSIONS: We found that the SCORE had the best balance between recall, precision, and AUC among the 6 screening tools that were compared among Malaysian postmenopausal women.
