Fetal autonomic malfunction as a marker of fetal distress in growth-restricted fetuses: three case reports
10.5468/ogs.2019.62.6.469
- Author:
Igor Victorovich LAKHNO
1
;
Schmidt ALEXANDER
Author Information
1. Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine. igorlakhno71@gmail.com
- Publication Type:Case Report
- Keywords:
Fetal distress;
Fetal growth restriction;
Embryonic and fetal development
- MeSH:
Brain;
Cardiotocography;
Electrocardiography;
Embryonic and Fetal Development;
Female;
Fetal Death;
Fetal Development;
Fetal Distress;
Fetus;
Heart Rate, Fetal;
Hemodynamics;
Methods;
Pregnancy;
Prospective Studies
- From:Obstetrics & Gynecology Science
2019;62(6):469-473
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fetal growth restriction (FGR) is characterized by fetal compromise and delayed neurological maturation. We report 3 cases of early FGR in the 26th week of gestation, based on hemodynamic Doppler monitoring, conventional cardiotocography, and non-invasive fetal electrocardiography (NI-FECG). Fetal heart rate variability (HRV), beat-to-beat variations, and fetal autonomic brain age scores (fABASs) were normal despite the absence of umbilical diastolic flow in the first case and the pregnancy continued to 30 weeks. NI-FECG helped achieve better fetal maturity. Fetal HRV and fABASs were low in the second and third cases. Fetal demise occurred soon in both cases. We conclude that NI-FECG could be a prospective method for the detection of fetal distress in early FGR.