A case of endometrial glassy cell carcinoma: a rare entity which necessitates of better understanding
10.5468/ogs.2019.62.6.478
- Author:
Clelia CALLEGARI
1
;
Paola ALGERI
;
Antonella BUZZI
;
Teresio MOTTA
;
Cinzia MANFREDINI
;
Sonia Maria ROTA
Author Information
1. Department of Obstetrics, Foundation MBBM, Monza, Italy. clelia.callegari@gmail.com
- Publication Type:Case Report
- Keywords:
Endometrial cancer;
Glassy cell carcinoma;
Uterine cancer
- MeSH:
Biopsy;
Cytoplasm;
Diagnosis;
Endometrial Neoplasms;
Endometrium;
Eosinophils;
Female;
Follow-Up Studies;
Glass;
Humans;
Hysterectomy;
Hysteroscopy;
Lymph Node Excision;
Middle Aged;
Papanicolaou Test;
Prognosis;
Uterine Neoplasms
- From:Obstetrics & Gynecology Science
2019;62(6):478-482
- CountryRepublic of Korea
- Language:English
-
Abstract:
Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in the endometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a ground glass appearance. Till date, only 14 cases of this carcinoma have been reported. In this report, we have described a case of EGCC to help define standard diagnostic criteria and better understand the course, ideal treatment, and accurate prognosis of this disease. We report a case of a 64-year-old woman diagnosed with EGCC after an abnormal pap smear. She underwent a hysteroscopy, which led to the histological diagnosis. Laparotomic total hysterectomy and bilateral salpingo-oophorectomy were performed with pelvic lymphadenectomy and peritoneal and omental biopsies. Final pathological examination confirmed the initial diagnosis. Pelvic nodes removed during surgery and peritoneal and omental biopsies were negative for tumor cells. Treatment was considered appropriate and the patient did not require additional therapies. She was subsequently assigned to clinical follow-up and is alive, with no evidence of the disease.
