The Potential of Centella asiatica (Linn.) Urban as an Anti-Microbial and Immunomodulator Agent: A Review
10.20307/nps.2019.25.2.92
- Author:
Nurul Hikmah HARUN
1
;
Abdi Wira SEPTAMA
;
Wan Amir Nizam WAN AHMAD
;
Rapeah SUPPIAN
Author Information
1. School of Health Sciences, Health Campus, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. heekmah85@gmail.com
- Publication Type:Review
- Keywords:
Anti-microbial;
Centella asiatica (Linn.) Urban;
immunomodulatory;
pegaga
- MeSH:
Centella;
Complex Mixtures;
Inflammation;
Malaysia;
Memory;
Plants;
Rheumatic Diseases;
Syphilis, Cutaneous;
Wound Healing
- From:Natural Product Sciences
2019;25(2):92-102
- CountryRepublic of Korea
- Language:English
-
Abstract:
Centella asiatica (Linn.) Urban (Umbelliferae) which is also known as ‘pegaga’ is highly consumed and eaten raw as ‘ulam’ in Malaysia. C. asiatica is used in traditional medicines to treat various health conditions such as rheumatism, inflammation, syphilis, skin diseases and diarrhoea. Various reports exhibited that the crude extracts and isolated bioactive compounds of C. asiatica possessed a broad range of pharmacological activities such as anti-oxidant, anti-diabetic, anti-tumor, wound healing, anti-microbial, anti-inflammatory, immunomodulatory, hepatoprotective and memory enhancing properties. The pharmacological validation on anti-microbial and immunomodulatory of C. asiatica is very limited and several existence review papers related for this plant had not been focused for both activities. This review therefore attempts to combine the existing literature to offer immense scope for researchers engaged in validation of the traditional claims and bioactivities of this plant related with anti-microbial and immunomodulatory potential.
