Analysis of Apparent Diffusion Coefficients of the Brain in Healthy Controls: A Comparison Study between Single-Shot Echo-Planar Imaging and Read-out-Segmented Echo-Planar Imaging
- Author:
Yangsean CHOI
1
;
Eo Jin HWANG
;
Yoonho NAM
;
Hyun Seok CHOI
;
Jinhee JANG
;
So Lyung JUNG
;
Kook Jin AHN
;
Bum soo KIM
Author Information
- Publication Type:Brief Communication
- Keywords: Apparent diffusion coefficient; Diffusion-weighted imaging; Single-shot echo-planar imaging; Read-out-segmented echo-planar imaging; Magnetic resonance imaging
- MeSH: Brain; Cerebrospinal Fluid; Diffusion; Echo-Planar Imaging; Gray Matter; Healthy Volunteers; Magnetic Resonance Imaging; Masks; White Matter
- From:Korean Journal of Radiology 2019;20(7):1138-1145
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To compare apparent diffusion coefficients (ADCs) of brain segments by using two diffusion-weighted imaging acquisition modes, single-shot echo-planar imaging (ss-EPI) and read-out-segmented echo-planar imaging (rs-EPI), and to assess their correlation and agreement in healthy controls. MATERIALS AND METHODS: T2-weighted (T2W) images, rs-EPI, and ss-EPI of 30 healthy subjects were acquired using a 3T magnetic resonance scanner. The T2W images were co-registered to the rs-EPI and ss-EPI, which were then segmented into the gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) to generate masking templates. ADC maps of rs-EPI and ss-EPI were also segmented into the GM, WM, and CSF by using the generated templates. ADCs of rs-EPI and ss-EPI were compared using Student's t tests and correlated using Pearson's correlation coefficients. Bland-Altman plots were used to assess the agreement between acquisitions.
