Multiparametric Functional Magnetic Resonance Imaging for Evaluating Renal Allograft Injury
- Author:
Yuan Meng YU
1
;
Qian Qian NI
;
Zhen Jane WANG
;
Meng Lin CHEN
;
Long Jiang ZHANG
Author Information
- Publication Type:Review
- Keywords: Multiparametric magnetic resonance imaging; Functional MRI; Kidney transplantation; Allograft fibrosis; Allograft dysfunction
- MeSH: Allografts; Diffusion; Fibrosis; Humans; Kidney Failure, Chronic; Kidney Transplantation; Magnetic Resonance Imaging; Oxygen; Perfusion; Quality of Life; Transplants
- From:Korean Journal of Radiology 2019;20(6):894-908
- CountryRepublic of Korea
- Language:English
- Abstract: Kidney transplantation is the treatment of choice for patients with end-stage renal disease, as it extends survival and increases quality of life in these patients. However, chronic allograft injury continues to be a major problem, and leads to eventual graft loss. Early detection of allograft injury is essential for guiding appropriate intervention to delay or prevent irreversible damage. Several advanced MRI techniques can offer some important information regarding functional changes such as perfusion, diffusion, structural complexity, as well as oxygenation and fibrosis. This review highlights the potential of multiparametric MRI for noninvasive and comprehensive assessment of renal allograft injury.
