A Novel Adenomatous Polyposis Coli Gene Mutation of Cribriform-Morular Variant Papillary Thyroid Carcinoma: A Case Report
10.3342/kjorl-hns.2017.00759
- Author:
Hee Jung KIM
1
;
Nayeon CHOI
;
Man Ki CHUNG
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. manki.chung@gmail.com
- Publication Type:Case Report
- Keywords:
APC gene mutation;
Cribriform-morular variant of papillary thyroid carcinoma;
Familial adenomatous polyposis
- MeSH:
Adenomatous Polyposis Coli;
Colonic Neoplasms;
Genes, APC;
Humans;
Thyroid Gland;
Thyroid Neoplasms
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2019;62(3):192-196
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cribriform-morular variant papillary thyroid carcinoma (CMV-PTC) is a rare cancer that may arise in patients with familial adenomatous polyposis (FAP). Adenomatous polyposis coli (APC) gene mutation is associated with FAP, which is known as a premalignant lesion of colon cancer. In this report, we report a 16 years old patient of CMV-PTC comorbid with FAP, which was related with a new type of APC gene mutation.
