A Case of Peripheral T-cell Lymphoma, Unspecified Presenting as Multiple Ulcerative Tumors
- Author:
Dong Uk CHEON
1
;
Ju Wang JANG
;
Sung Soo HAN
;
Hyun Min SEO
;
Joung Soo KIM
Author Information
1. Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea. tuentuen@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Peripheral T-cell lymphoma;
Unspecified
- MeSH:
Aged;
Classification;
Dermis;
Granzymes;
Humans;
Lymphocytes;
Lymphoma, T-Cell;
Lymphoma, T-Cell, Peripheral;
Neck;
T-Lymphocytes;
Ulcer;
Upper Extremity
- From:Korean Journal of Dermatology
2019;57(3):152-155
- CountryRepublic of Korea
- Language:English
-
Abstract:
Peripheral T cell lymphoma, unspecified (PTCL-U) comprises a heterogenous group of mature T-cell lymphomas that do not match with any defined T-cell entities in the current classification system. A 68-year-old man presented with extensive erythematous to brownish ulcerative tumors with yellowish discharge on the neck, trunk, and both upper extremities that had persisted for the past 7 months. Histological findings showed medium- to large-sized pleomorphic lymphocytes with cellular atypia infiltrating the deep dermis and subcutis. Immunohistochemical analysis of specimens from this patient revealed positive staining for CD2, CD45, and granzyme B and mildly positive staining for CD3, CD4, CD30, and CD79a. Based on these clinico-pathological findings, the patient was finally diagnosed with PTCL-U. We report herein a rare case of PTCL-U presenting as multiple ulcerative tumors.
