A Case of Cicatricial Pemphigoid with Autoantibodies Against the BP180 and BP230 Antigens.
- Author:
Yae Lee CHUNG
1
;
Joo Young KIM
;
Soo Chan KIM
Author Information
1. Department of Dermatology, Yonsei University College of Medicine Seoul, Korea.
- Publication Type:Case Report
- MeSH:
Autoantibodies*;
Blister;
Cicatrix;
Collagen Type VII;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Laminin;
Mucous Membrane;
Pemphigoid, Benign Mucous Membrane*
- From:Korean Journal of Dermatology
2000;38(10):1370-1374
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cicatricial pemphigoid is a chronic autoimmune subepithelial blistering disease that predominantly involves mucous membrane with resultant scar formation. It may involve oral, ocular, nasal, pharyngeal, laryngeal, esophageal, and anogenital mucous membranes. Cicatricial pemphigoid is a heterogenous group of diseases with respect to the autoimmune target antigens including BP180(type XVII collagen), BP230, laminin 5(epiligrin), laminin 6, type VII collagen and other newly described antigen. We describe a patient with cicatricial pemphigoid in whom circulating IgA and IgG autoantobodies against BP180 and BP230 antigens were detected simunltaneously.
