Blood Management Protocol without Transfusion in Orthopedic Surgery
10.17945/kjbt.2019.30.1.15
- Author:
You Sung SUH
1
;
Jeong Jae LEE
;
Jae Hwi NHO
;
Haran CHUNG
;
Won Seok LEE
;
Byung Woong JANG
;
Yong Beom KIM
;
Dong Il CHUN
;
Sung Woo CHOI
;
Jae Chul LEE
;
Hyung Suk CHOI
Author Information
1. Department of Orthopaedic Surgery, Soonchunhyang University Hospital Seoul, Seoul, Korea. huuy@schmc.ac.kr
- Publication Type:Review
- Keywords:
Orthopaedic surgery;
Patient blood management;
Transfusion;
Erythropoietin;
Tranexamic acid
- MeSH:
Drainage;
Erythropoietin;
Humans;
Iron;
Orthopedics;
Plasma;
Tranexamic Acid;
Venous Thromboembolism
- From:Korean Journal of Blood Transfusion
2019;30(1):15-22
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We developed a new blood management protocol that allows patients to not undergo transfusion during major orthopaedic surgery. Here, we report the safety of or our protocol. The preoperative pharmacological protocol consisted of the administration of 40 µg of recombinant erythropoietin subcutaneously and 100 mg of iron supplements intravenously. During the operation, reinfusion of drainage blood using a cell saver and plasma expander was used. The cell saver device passed the collected blood through a filter, which washed the blood, removing the hemolyzed cells and other impurities. Intravenous tranexamic acid 1 g is given just before the operation, except high-risk patients for venous thromboembolism. Postoperatively, recombinant erythropoietin and iron supplements were administered in the same manner with the preoperative protocol and continued until a hemoglobin level reached 10 g/dL.