Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
- Author:
Pinar Yilgor HURI
1
;
Seren HAMSICI
;
Emre ERGENE
;
Gazi HURI
;
Mahmut Nedim DORAL
Author Information
- Publication Type:Review
- Keywords: Knee; Fat pad; Stem cell
- MeSH: Adipose Tissue; Knee; Knee Injuries; Orthopedics; Regeneration; Stem Cells
- From:The Journal of Korean Knee Society 2018;30(3):179-186
- CountryRepublic of Korea
- Language:English
- Abstract: Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) possess enhanced and age-independent differentiation capacity as compared to other stem cells, which makes them a very promising candidate in stem cell-based regenerative therapy. The aims of this review are to outline the latest advances and potential trends in using IPFP-ASCs and to emphasize the advantages over other sources of stem cells for applications in orthopedic surgery.
